BDBM369334 N-[(1S)-1-(3-chlorophenyl)ethyl]-4-[6-(2- methoxy-4-pyridyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-2,2-dimethyl-piperazine-1- carboxamide::US10227357, Compound P-0650

SMILES COc1cc(ccn1)-c1cc2c(ncnc2[nH]1)N1CCN(C(=O)N[C@@H](C)c2cccc(Cl)c2)C(C)(C)C1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369334   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Plexxikon

US Patent
LigandPNGBDBM369334(N-[(1S)-1-(3-chlorophenyl)ethyl]-4-[6-(2- methoxy-...)
Affinity DataKi:  5.50E+3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent